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Symbol
Name
ID
Jak2
Janus kinase 2
MGI:96629
Phenotype annotations related to cardiovascular system
Darker colors indicate more annotations
Human Phenotypes
Gastrointestinal hemorrhage
Cerebral hemorrhage
Bruising susceptibility
Purpura
Peripheral arterial stenosis
Abnormal cerebral vascular morphology
Ischemic stroke
Transient ischemic attack
Hypertension
Cerebral ischemia
Pulmonary arterial hypertension
Budd-Chiari syndrome
Myocardial infarction
Syncope
Splenomegaly
Disease(s) Associated with JAK2
Budd-Chiari syndrome
essential thrombocythemia
familial erythrocytosis 1
myelofibrosis
polycythemia vera

Mouse Phenotypes
abnormal blood vessel morphology
increased heart rate
Availability Mouse Genotype
Jak2tm1.1Ble/Jak2+
Commd10Tg(Vav1-icre)A2Kio/Commd10+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory